# Confirmatory Adaptive Clinical Trial Design and Analysis

## Documentation for package ‘rpact’ version 3.5.1

- DESCRIPTION file.
- User guides, package vignettes and other documentation.
- Package NEWS.

## Help Pages

rpact-package | rpact - Confirmatory Adaptive Clinical Trial Design and Analysis
as251Normal | Algorithm AS 251: Normal Distribution
as251StudentT | Algorithm AS 251: Student T Distribution
getAccrualTime | Get Accrual Time
getAnalysisResults | Get Analysis Results
getAvailablePlotTypes | Get Available Plot Types
getClosedCombinationTestResults | Get Closed Combination Test Results
getClosedConditionalDunnettTestResults | Get Closed Conditional Dunnett Test Results
getConditionalPower | Get Conditional Power
getConditionalRejectionProbabilities | Get Conditional Rejection Probabilities
getData | Get Simulation Data
getData.SimulationResults | Get Simulation Data
getDataSet | Get Dataset
getDataset | Get Dataset
getDesignCharacteristics | Get Design Characteristics
getDesignConditionalDunnett | Get Design Conditional Dunnett Test
getDesignFisher | Get Design Fisher
getDesignGroupSequential | Get Design Group Sequential
getDesignInverseNormal | Get Design Inverse Normal
getDesignSet | Get Design Set
getEventProbabilities | Get Event Probabilities
getFinalConfidenceInterval | Get Final Confidence Interval
getFinalPValue | Get Final P Value
getGroupSequentialProbabilities | Get Group Sequential Probabilities
getHazardRatioByPi | Survival Helper Functions for Conversion of Pi, Lambda, Median
getLambdaByMedian | Survival Helper Functions for Conversion of Pi, Lambda, Median
getLambdaByPi | Survival Helper Functions for Conversion of Pi, Lambda, Median
getMedianByLambda | Survival Helper Functions for Conversion of Pi, Lambda, Median
getMedianByPi | Survival Helper Functions for Conversion of Pi, Lambda, Median
getNumberOfSubjects | Get Number Of Subjects
getObjectRCode | Get Object R Code
getObservedInformationRates | Get Observed Information Rates
getOutputFormat | Get Output Format
getPerformanceScore | Get Performance Score
getPiByLambda | Survival Helper Functions for Conversion of Pi, Lambda, Median
getPiByMedian | Survival Helper Functions for Conversion of Pi, Lambda, Median
getPiecewiseExponentialDistribution | The Piecewise Exponential Distribution
getPiecewiseExponentialQuantile | The Piecewise Exponential Distribution
getPiecewiseExponentialRandomNumbers | The Piecewise Exponential Distribution
getPiecewiseSurvivalTime | Get Piecewise Survival Time
getPowerAndAverageSampleNumber | Get Power And Average Sample Number
getPowerCounts | Get Power Counts
getPowerMeans | Get Power Means
getPowerRates | Get Power Rates
getPowerSurvival | Get Power Survival
getRawData | Get Simulation Raw Data for Survival
getRepeatedConfidenceIntervals | Get Repeated Confidence Intervals
getRepeatedPValues | Get Repeated P Values
getSampleSizeCounts | Get Sample Size Counts
getSampleSizeMeans | Get Sample Size Means
getSampleSizeRates | Get Sample Size Rates
getSampleSizeSurvival | Get Sample Size Survival
getSimulationEnrichmentMeans | Get Simulation Enrichment Means
getSimulationEnrichmentRates | Get Simulation Enrichment Rates
getSimulationEnrichmentSurvival | Get Simulation Enrichment Survival
getSimulationMeans | Get Simulation Means
getSimulationMultiArmMeans | Get Simulation Multi-Arm Means
getSimulationMultiArmRates | Get Simulation Multi-Arm Rates
getSimulationMultiArmSurvival | Get Simulation Multi-Arm Survival
getSimulationRates | Get Simulation Rates
getSimulationSurvival | Get Simulation Survival
getStageResults | Get Stage Results
getTestActions | Get Test Actions
kable | Create tables in Markdown
kable.ParameterSet | Create output in Markdown
knit_print.ParameterSet | Print Parameter Set in Markdown Code Chunks
knit_print.SummaryFactory | Print Summary Factory in Markdown Code Chunks
mvnprd | Original Algorithm AS 251: Normal Distribution
mvstud | Original Algorithm AS 251: Student T Distribution
plot.AnalysisResults | Analysis Results Plotting
plot.Dataset | Dataset Plotting
plot.EventProbabilities | Event Probabilities Plotting
plot.NumberOfSubjects | Number Of Subjects Plotting
plot.ParameterSet | Parameter Set Plotting
plot.SimulationResults | Simulation Results Plotting
plot.StageResults | Stage Results Plotting
plot.SummaryFactory | Summary Factory Plotting
plot.TrialDesign | Trial Design Plotting
plot.TrialDesignCharacteristics | Trial Design Plotting
plot.TrialDesignPlan | Trial Design Plan Plotting
plot.TrialDesignSet | Trial Design Set Plotting
plotTypes | Get Available Plot Types
ppwexp | The Piecewise Exponential Distribution
print.SummaryFactory | Summary Factory Printing
print.TrialDesignCharacteristics | Trial Design Characteristics Printing
qpwexp | The Piecewise Exponential Distribution
rcmd | Get Object R Code
readDataset | Read Dataset
readDatasets | Read Multiple Datasets
rpact | rpact - Confirmatory Adaptive Clinical Trial Design and Analysis
rpwexp | The Piecewise Exponential Distribution
setOutputFormat | Set Output Format
testPackage | Test Package
utilitiesForPiecewiseExponentialDistribution | The Piecewise Exponential Distribution
utilitiesForSurvivalTrials | Survival Helper Functions for Conversion of Pi, Lambda, Median
writeDataset | Write Dataset
writeDatasets | Write Multiple Datasets