Package: ruv
Title: Detect and Remove Unwanted Variation using Negative Controls
Description: Implements the 'RUV' (Remove Unwanted Variation) algorithms.  These algorithms attempt to adjust for systematic errors of unknown origin in high-dimensional data.  The algorithms were originally developed for use with genomic data, especially microarray data, but may be useful with other types of high-dimensional data as well.  These algorithms were proposed in Gagnon-Bartsch and Speed (2012) <doi:10.1093/nar/gkz433>, Gagnon-Bartsch, Jacob and Speed (2013), and Molania, et. al. (2019) <doi:10.1093/nar/gkz433>.  The algorithms require the user to specify a set of negative control variables, as described in the references.  The algorithms included in this package are 'RUV-2', 'RUV-4', 'RUV-inv', 'RUV-rinv', 'RUV-I', and RUV-III', along with various supporting algorithms.  
Version: 0.9.7.2
Date: 2026-08-04
Imports: stats, ggplot2, scales, gridExtra
Suggests: shiny, colourpicker
Authors@R: person(given = "Johann",
                    family = "Gagnon-Bartsch",
                    role = c("aut", "cre"),
                    email = "johanngb@umich.edu")
License: GPL
URL: http://www-personal.umich.edu/~johanngb/ruv/
LazyLoad: yes
NeedsCompilation: yes
Packaged: 2026-08-31 20:04:19 UTC; johann
Author: Johann Gagnon-Bartsch [aut, cre]
Maintainer: Johann Gagnon-Bartsch <johanngb@umich.edu>
Repository: CRAN
Date/Publication: 2026-08-31 22:00:08 UTC
Built: R 4.5.3; x86_64-w64-mingw32; 2026-09-01 09:16:35 UTC; windows
Archs: x64
