News for Package nmw

Version 0.3.1 (2026-06-09)

• SumOut() bug fix: the line RunFolders <- MatchEnd(Folders, RunExt) previously assigned the logical vector returned by MatchEnd() to RunFolders instead of using it as a mask to subset Folders. This caused strsplit() inside GetModelNames() to fail with "non-character argument" whenever any run folders were present. Now RunFolders <- Folders[MatchEnd(Folders, RunExt)].

• SumOut() default RunExt changed from ".R75" to ".R76" to match NONMEM 7.6 (the current production release). Users on NONMEM 7.5 should pass RunExt = ".R75" explicitly.

• SumOut() now warns and returns invisible(NULL) when no matching run folders are found, instead of erroring on a zero-length loop.

• GetProbVal() bug fix: grep(Tag, PROB) returns integer(0) when the requested tag (e.g. "P:" or "F:") is absent — for example when the $PROB record is longer than 80 characters and NM-TRAN truncates it inside the FCON file, dropping the tag. The previous if (Loc > 0) test raised "argument is of length zero". The test was changed to if (length(Loc) > 0 && Loc[1] > 0), returning an empty string when the tag is absent.

• man/SumOut.Rd updated to reflect the new default RunExt and a richer description of the return value.

• MatchEnd() bug fix: replaced for (i in 1:n) with for (i in seq_len(n)) so that calling on an empty character vector no longer iterates over c(1, 0) and tries to read NA elements.

• Regression tests added in tests/testthat/test-utils_data.R covering the SumOut() empty-folder, GetProbVal() missing-tag, and MatchEnd() empty-input cases.

• report_ebe() (S5 “ETA vs Categorical Variables”) bug fix: when the number of ETAs times the number of categorical covariates produced a panel grid too dense for boxplot margins, plot.new() raised “figure margins too large” and the PDF was truncated mid-page. The categorical-covariate panels are now split across multiple PDF pages (cap of ~35 panels per page, configurable through the internal MAX_CELLS_PER_PAGE constant), with page numbers appended to the panel title when more than one page is produced.

Version 0.3.0 (2026-05-08)

• General-purpose helpers for NONMEM dataset construction added (build_nm_dataset, build_dose_records, build_obs_records).

• Time-varying covariate merge by LOCF/LOCB: locf_value, merge_cov_locf.

• Datetime parsers: parse_dtc, dat2_time_to_posix.

• Coding helpers: code_sex, code_race.

• Cockcroft-Gault CRCL: crcl_cg, add_crcl_cg.

• Mass to molar unit conversion: nm_to_molar.

Version 0.2.0 (2026-03-08)

• Post-run processing of NONMEM output with PDF diagnostic reports merged from nma package.

• 8 report types: OFV, Parameters, Predictions, Residuals, EBE, Input, Output, IndiPK.

• New utility functions for NONMEM data processing and parsing.

• Switched from exportPattern to explicit exports in NAMESPACE.

Version 0.1.6 (2026-03-08)

• Typos in documentation corrected.

Version 0.1.5 (2023-05-09)

• AddCox function for adding a covariate to existing NONMEM dataset.

• CombDmExPc function for combining demographics(DM), dosing(EX), and DV(PC) tables.

• TrimOut function to beautify the original NONMEM OUTPUT

• Errata in manual corrected.

Version 0.1.4 (2018-04-10)

• Errata in manual corrected.

Version 0.1.3 (2017-10-23)

• TabStep() is added.

• Speed is increased.

• References are updated.

• Vignette is updated.

Version 0.1.2 (2017-10-20)

• This package will be used at the workshop on 2017-10-25 at Kyoto Japan 1st APC satellite workshop.

• Bug at calculating objective function value for "LAPL" method is fixed.

• Bug at scaling other than zero lower bound transformation fixed.

Version 0.1.1 (2017-03-14)

• This package will be used at the workshop within US FDA on 2017-03-21.

• For the initialization step, Pred function name should be given by the user. It does not read directly from the file any more.

Version 0.1.0 (2017-02-21)

• This package was born and used at the Workshop held by Kyun-Seop Bae MD PhD <k@acr.kr>.

• InitStep used Pred function within a file.